For better absorption the drug must be taken with a full glass of water. In 30% of cases Doxycycline causes upset stomach, unfortunately. In this case the dosage is advised to be taken with a small amount of food or a glass of milk. But mind that such a way of intake may reduce the efficacy of the drug, and thus you will need to take a longer course of treatment. During the treatment course of Doxycycline it is recommended to keep to a low-calcium diet as high content of calcium in foods or taking additional calcium in food supplements and vitamin complexes decrease the efficacy of the medicine. Other elements which can affect the efficacy of Doxycycline are aluminim, magnesium, iron, zinc and other vitamins and micro-elements. Doxycycline is also administered for prevention and in the treatment schemes of the next conditions and cases:  direct exposure to sexually passed diseases in case of sexual assault  inflammations of mouth cavity (gums in particular)  unexplained inflammations of mouth cavity and around teeth  arthritis developed in course of Lyme disease  dilation of blood vessels in eye balls  intestine inflammations of unexplained nature This spectrum of usage proves that Doxycycline can be used safely for prevention and treatment of various diseases and conditions. How to take Doxycycline correctly for the highest efficiency Doxycycline is best taken by mouth. To ensure the best absorption and fast delivery to the blood, the drug is recommended to be taken on empty stomach. Take a pill an hour prior to meals ot at least two hours later after meals. It does not matter whether you take a whole dosage of the drug at a time or split your daily dosage for several intakes. However taking the medicine in lower dosages and more frequently will reduce the risk of possible side effects which are commonly related to the Doxycycline treatment.

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Em homens, a média da concentração plasmática máxima de sildenafila livre, após a administração de uma dose única oral de 100 mg, é de aproximadamente 18 ng/mL ou 38 nM.

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